Nikolaj Gadegaard FRSE is a Professor of Biomedical Engineering and the Director of Research in the School of Engineering at the University of Glasgow. With an educational background in Chemistry, Physics, and Biophysics, and having worked at the interface of physics/engineering and biology for more than two decades, he is an expert on the use of micro- and nanofabrication technologies for biomedical applications with a particular focus in using injection moulding for sample preparation. The group is implementing the latest advances in AI for image analyses and correlation to biological functions. He has published 200 papers in e.g. Nature family journals, Advanced Materials, ACS Nano, and JACS with more than 18,000 citations and an h-index of 57. In 2015, he was awarded an ERC consolidator grant (FAKIR) to study the cellular dynamics of cells on nanostructured materials. This work combines precision engineering with state-of-the-art super-resolution microscopy and FRET imaging for spatial mapping and mechanotransduction events, respectively.
Contributions to the project
The group in Glasgow will lead the development and implementation of AI in image analysis, data fusion, and control loop integration. Through the consortium, they will develop the integration of different imaging modalities delivered by the partners to provide cell-specific identification and real-time analysis of the gastruloids. The information will then be used to develop a closed-loop system for the supervised development of gastruloids.